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Cytotoxicity of Paclitaxel Incorporated in PLGA Nanoparticles on Hypoxic Human Tumor Cells

✍ Scribed by Cheng Jin; Ling Bai; Hong Wu; Wenjie Song; Guozhen Guo; Kefeng Dou


Publisher
Springer US
Year
2009
Tongue
English
Weight
331 KB
Volume
26
Category
Article
ISSN
0724-8741

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Cytotoxicity of Paclitaxel Incorporated
✍ Cheng Jin; Ling Bai; Hong Wu; Wenjie Song; Guozhen Guo; Kefeng Dou πŸ“‚ Article πŸ“… 2009 πŸ› Springer US 🌐 English βš– 331 KB

## Purpose: The aim of this work was to prepare paclitaxel-loaded plga nanoparticles and determine cytotoxicity of released paclitaxel for two hypoxic human tumor cell lines: breast carcinoma (mcf-7) and carcinoma cervicis (hela). ## Methods: Poly(d,l-lactide-co-glycolide) (plga) nanoparticles co