๐”– Bobbio Scriptorium
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Cytotoxic T cell responses to intracellular pathogens

โœ Scribed by Steffen Stenger; Robert L Modlin

Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
943 KB
Volume
10
Category
Article
ISSN
0952-7915

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โœฆ Synopsis

Host defense against intracellular pathogens is thought to require cytotoxic T cells. Recent studies have investigated the impact of host cell lysis and cytokine production by cytotoxic T lymphocytes on the fate of intracellular pathogens. The identification of two mechanisms of lysis induced by cytotoxic T lymphocytes--the granule exocytosis pathway and the Fas-FasL interaction--have provided new insight into the role of cytotoxic T lymphocyters in immunity to infection.

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