Cytotoxic T cell responses to haptenated cells II. On the role of H-2 genes
β Scribed by Werner Haas; Helmut Pohlit; Harald von Boehmer
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 682 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0014-2980
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## Abstract The present study investigates the role of nonβHβ2 genes in controlling generation of the Hβ2βrestricted, T cellβmediated cytotoxic response against trinitrophenyl (TNP)βmodified syngeneic cells (TNPβself). Spleen cells from C3H/He (Hβ2^k^) or B10.BR (Hβ2^k^) normal mice or from mice pr
It has previously been reported (Hiinig, T. et al., Eur. J. Zmmunol. 1983. 13: 1) that highly purified peripheral T cells do not respond to concanavalin A (Con A) even in the presence of Con A-induced spleen cell supernatant as a source of interleukin 2 (IL 2). In the present report, the hypothesis