𝔖 Bobbio Scriptorium
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Cytotoxic effector cells with the characteristics of natural killer cells in the lungs of mice

✍ Scribed by Paolo Puccetti; Angela Santoni; Carlo Riccardi; Ronald B. Herberman

Publisher
John Wiley and Sons
Year
1980
Tongue
French
Weight
551 KB
Volume
25
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

Cells with in vitro cytotoxicity against tumor targets in a short‐term ^51^Cr release assay have been recovered from the lungs of mice that were either untreated or injected with biological or synthetic agents 1–3 days earlier. The cytotoxic effector cells were non‐adherent, non‐phagocytic and shared many characteristics with splenic natural killer (NK) cells. This finding is discussed with particular regard to our previous observations on the rapid in vivo elimination from the lungs of intravenously injected, radiolabelled tumor cells.

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