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Cytotoxic effect of anti-lymphocytic globulin on leukaemic myeloblasts

✍ Scribed by M.F. Heyworth; S.C. Truelove

Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
230 KB
Volume
1
Category
Article
ISSN
0165-2478

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Cytotoxic and DNA synthesis inhibitory effects of several iron chelators with different physicochemical properties have been tested in four myeloid leukaemic cell lines (U937, K562, ML2 and HL60). The small lipophilic chelators 8-hydroxyquinoline, tropolone an5d omadine at 2 x lo-%, caused substanti