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Cytosine Derived Heteroadduct Formation in Ultraviolet-irradiated DNA

โœ Scribed by VARGHESE, A. J.; PATRICK, M. H.

Book ID
109668375
Publisher
Nature Publishing Group
Year
1969
Tongue
English
Weight
204 KB
Volume
223
Category
Article
ISSN
0028-0836

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Both ultraviolet irradiation and oxidation of DNA produce a variety of pyrimidine base damages. A human endonuclease recognizes such altered bases on these DNA substrates. This human endonuclease incises ultraviolet-irradiated DNA exclusively at sites of photochemically modified cytosines. The preci