Cytosine arabinoside and 6-thioguanine in the treatment of childhood acute myeloblastic leukemia
โ Scribed by Hernan Moreno; Robert P. Castleberry; William P. McCann
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 590 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
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Eighteen children with acute myeloid leukemia have been treated with a fourdrug protocol using cytosine arabinoside, daunorubicin, prednisolone, and mercaptopurine or thioguanine. The initial remission rate overall was 78%. Of 15 children who completed a week's treatment, i.e. one complete cycle, 14
One hundred patients were entered in a cooperative study comparing the efficacy of two different regimens in the induction treatment of acute nonlymphocytic leukemia (ANLL). Patients were randomly allocated to receive either the DAT or VAT combination; half of the patients were also randomized to re
One hundred-sixty-three children with acute nonlymphocytic leukemia (ANLL) were treated with a multiple-drug induction program (PATCO) consisting of prednisone (PDN), cytosine arabinoside ((Ara-C), 6-thioguanine (6-TG), cyclophosphamide (CPM), and Oncovin (VCR). Ninety-six, 59%, obtained a remission