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Cytomegalovirus as a frequent cause of Guillain-Barré syndrome

✍ Scribed by H. Schmitz; G. Enders

Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
371 KB
Volume
1
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

In 10 patients with Guillain‐Barré syndrome a preceeding cytomegalovirus infection could be demonstrated by virus‐specific IgM antibodies that were present in high titers in 9 of the 10 patients in the first serum specimen. The IgM antibodies to cytomegalovirus were detected by a sensitive “double” indirect immunofluorescence technique. In most of our cases (8 of 10) the complement‐fixing antibody titers had already reached high levels on admission into a hospital, and significant titer changes were not observed. Cytomegalovirus was isolated from the urine of five patients.

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