minimal, 25 had mild, 26 had moderate, and 4 had severe chronic Osaka, Japan; and the Department of Microbiology and Immunology, Aichi Medical Univerhepatitis. 25 Three moderate and two severe chronic hepatitis cases sity School, Aichi, Japan. were observed in the five patients with chronic hepatit
Cytolytic T cell clones derived from liver tissue of patients with chronic hepatitis B
✍ Scribed by Robert M. Hoffmann; Gerd R. Pape; Peter Richer; Josef Eisenburg; Jutta Dohrmann; Reinhart Zachoval; Gustav Paumgartnei; Gert Riethmüller
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 428 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Cells expressing alpha- and gamma-interferon were localized in the liver tissue of patients with chronic hepatitis B by means of light and electron microscopy using monoclonal antibodies. Interferon-positive cells were regularly seen in the infiltrating mononuclear cells, and the number showed a goo
## Abstract Epigenetic factors may modulate chronic Hepatitis B viral infection by affecting virion gene transcription. The aim of this study was to compare the methylation status of the intrahepatic covalently closed circular DNA (cccDNA) CpG island 2 and HBV replication capability. HBV cccDNA was
## Abstract ## Objective The association of hepatitis C virus (HCV) infection with type II mixed cryoglobulinemia is well established, but the role of HCV in B cell lymphoma remains controversial. The objective of this study was to determine the frequency of circulating and liver‐infiltrating mono
## Objective: To determine the structure of t cell receptors (tcr) used by sm-b-reactive human t cell clones, to map t cell epitopes on the sm-b autoantigen, and to determine the hla restriction element used in the recognition of sm-b by t cells. ## Methods: Sm-b-reactive t cell clones were gener
The hypervariable domain (HVRI) within the Nterminus of the E2 protein of hepatitis C virus (HCV) is known to be variable antigenically during the course of persistent infection. The aim of the study was to detect B-cell epitopes in HVRI responsible for neutralizing HCV. The B-cell epitopes were ana