Cytologic findings after fertility-sparing radical trachelectomy

✍ Scribed by Feratovic, Rusmir ;Lewin, Sharyn N. ;Sonoda, Yukio ;Park, Kay J. ;Abu-Rustum, Nadeem R. ;Moreira, Andre L. ;Lin, Oscar

• Book ID: 102109362
• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 161 KB
• Volume: 114
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/cncr.23256

✦ Synopsis

BACKGROUND. Radical trachelectomy is a surgical procedure intended to preserve fertility in patients with early-stage cervical carcinoma in which the cervix is amputated in continuity with the parametrium and upper vagina, thereby sparing the uterus and adnexa. Follow-up is performed with periodic cytology specimens. The objective of the current study was to analyze the cytologic findings after this novel procedure.

METHODS.

Isthmic and vaginal Papanicolaou-stained ThinPrep cytology specimens taken from patients after radical vaginal and abdominal trachelectomy were reviewed. The specimens were also analyzed for the presence of benign endocervical cells, lower uterine segment glandular cells, endometrial stromal cells, and endometrial cells. The findings were correlated with the original diagnosis and follow-up, which included subsequent cytology specimens and biopsies.

Dr. Sonoda has acted as a Speaker for Genzyme and has received an educational grant from Plasma Surgical.