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Cytokines and the acute phase response in post-treatment reactive encephalopathy of Trypanosoma brucei brucei infected mice

✍ Scribed by P.David Eckersall; John W Gow; Christopher McComb; Barbara Bradley; Jean Rodgers; Maxwell Murray; Peter G.E Kennedy


Book ID
119604139
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
660 KB
Volume
50
Category
Article
ISSN
1383-5769

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Trypanosoma brucei brucei (Tbb) infection is a model of chronic immune response associated with severe neurological disorders believed to lead to coma and death. We hypothesized that exaggerated production of proinflammatory molecules within the cental nervous system (CNS) may be involved in the eti