✦ LIBER ✦

Cytokine receptors

✍ Scribed by Steven Gillis

Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 602 KB
Volume: 3
Category: Article
ISSN: 0952-7915
DOI: 10.1016/0952-7915(91)90030-5

No coin nor oath required. For personal study only.

✦ Synopsis

The molecular characterization of cytokine receptors has progressed rapidly over the past 5 years as a result of availability of radiolabeled cytokines, as well as the identification or creation of cell lines that express significant numbers of receptors at the cell surface. This explosion in research effort has led to establishment of multiple cytokine-receptor gene families and the realization that inhibition of cytokine function at the level of ligand-receptor interaction may be an important area for therapeutic drug development.

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