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Cytokine profile in acute myelofibrosis associated with aggressive large granular lymphocyte leukemia

✍ Scribed by Dr. Bakul I. Dalal; Paul A. Keown; Frixos Paraskevas; Gaynor Williams; James B. Johnston


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
325 KB
Volume
49
Category
Article
ISSN
0361-8609

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## Abstract As a rule, T cell large granular lymphocyte (T‐LGL) leukemia runs a chronic clinical course without need for therapy. Some cases, however, progress to an aggressive disease after the indolent clinical stage. The transformation mechanism into a high‐grade malignancy has not been well stu