Cytokine production by normal human astrocytes in culture
โ Scribed by F. Aloisi; G. Borsellino; U. Testa; A. Care; C. Peschle; G. Levi
- Book ID
- 119107917
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 78 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0165-5728
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๐ SIMILAR VOLUMES
Reactive nitrogen intermediates, such as nitric oxide (NO), play an important role in host-defense and injury. Human astrocytes released abundant NO upon stimulation with the pro-inflammatory cytokine interleukin (IL)-lp, which was potentiated by interferon (1FN)-y and tumor necrosis factor (TNFI-a.
Macrophage inflammatory protein-1alpha (MIP-1alpha) is a member of a superfamily of inflammatory cytokines termed chemokines, and it has been implicated in the pathogenesis of several human diseases with inflammatory components. It has been known that MIP-1alpha plays a role in recruiting and activa