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Cytokine production by dendritic cells genetically engineered to express IL-4: induction of Th2 responses and differential regulation of IL-12 and IL-23 synthesis

✍ Scribed by D Fox, Y Morita, R Gupta, K Seidl, K McDonagh


Book ID
120708074
Publisher
BioMed Central
Year
2003
Tongue
English
Weight
554 KB
Volume
5
Category
Article
ISSN
1478-6354

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Cytokine production by dendritic cells g
✍ Yoshitaka Morita; Raj Gupta; Kelly M. Seidl; Kevin T. McDonagh; David A. Fox πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 173 KB πŸ‘ 1 views

## Abstract Dendritic cells (DCs) retrovirally transduced with IL‐4 have recently been shown to inhibit murine collagen‐induced arthritis and associated Th1 immune responses __in vivo__, but the mechanisms that underly these effects are not yet understood. In this report we demonstrate that IL‐4‐tr