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Cytokine-mediated antitumor effect of bacillus Calmette-Guérin on tumor cells in vitro

✍ Scribed by Hiroaki Kurisu; Hideyasu Matsuyama; Yasukazu Ohmoto; Tomoyuki Shimabukuro; Katsusuke Naito

Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
602 KB
Volume
39
Category
Article
ISSN
0340-7004

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The cytolytic and anti-proliferative effects of bacillus Calmette-Gue ´rin (BCG) and/or interferon-a-2b (IFN-a-2b) on 5 human bladder carcinoma cell lines, RT4, RT112, MGH, SD and J82, were determined. The cell lines showed different sensitivities to BCG and IFN-a-2b. BCG had direct dosedependent cy