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Cytokine-induced nitric oxide inhibits mitochondrial energy production and induces myocardial dysfunction in endotoxin-treated rat hearts

✍ Scribed by Tetsuya Tatsumi; Kazuko Akashi; Natsuya Keira; Satoaki Matoba; Akiko Mano; Jun Shiraishi; Satoshi Yamanaka; Miyuki Kobara; Nobuhiro Hibino; Satoru Hosokawa; Jun Asayama; Shinji Fushiki; Henry Fliss; Masao Nakagawa; Hiroaki Matsubara


Book ID
116983545
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
698 KB
Volume
37
Category
Article
ISSN
0022-2828

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Amphotericin B potentiates the activatio
✍ Vladimir Trajkovic; Milos Markovic; Tatjana Samardzic; Djordje J. Miljkovic; Dus πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 183 KB

## Abstract Because the neurotoxic effects of the antifungal drug amphotericin B (AMB) closely resemble those ascribed to the highly reactive gaseous free radical nitric oxide (NO), we investigated the effect of AMB on NO production in rodent astrocytes. AMB caused a dose‐dependent increase of NO g