Cytogenetics of juvenile type chronic granulocytic leukemia
β Scribed by Susumu Inoue; Y. Ravindranath; Ruby I. Thompson; Wolf W. Zuelzer; Mark J. Ottenbreit
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 553 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0008-543X
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π SIMILAR VOLUMES
The juvenile type of "chronic myelogenous" leukemia (CMLJT) is a rare disease with only 40 cases reported to date. Clearly distinguishable from adult CML on both clinical and laboratory grounds, is is often confused with "congenital" leukemia, pseudoleukemia, leukemoid reactions or chronic granuloma
Three cases of megakaryoblastic transformation of chronic granulocytic leukemia (CGL) are reported. In each case, the leukemic transformation had morphologic features suggesting megakaryocytic differentiation. This was confirmed by positive immunostaining with a monoclonal antibody (HP1-1D) specific