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Cytogenetic study in spermatocytes of mice and Chinese hamsters after treatment with isoniazid (INH)

✍ Scribed by I. -D. Adler; A. Schmaltz; R. Rathenberg; D. Müller; F. F. Strasser; R. Perret


Publisher
Springer
Year
1978
Tongue
English
Weight
192 KB
Volume
42
Category
Article
ISSN
0340-6717

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✦ Synopsis


Meiotic chromosomes of spermatocytes from INH-treated male mice and Chinese hamsters were analysed for chromosome aberrations in diakinesis-metaphase I and metaphase II. The experiments were performed in two laboratories while a third laboratory participated in the chromosome evaluation. No enhancement of chromosome aberrations could be observed after acute treatment of early primary spermatocytes or chronic treatment of spermatogonia with INH.


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