Cytogenetic study in spermatocytes of mice and Chinese hamsters after treatment with isoniazid (INH)
✍ Scribed by I. -D. Adler; A. Schmaltz; R. Rathenberg; D. Müller; F. F. Strasser; R. Perret
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 192 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
✦ Synopsis
Meiotic chromosomes of spermatocytes from INH-treated male mice and Chinese hamsters were analysed for chromosome aberrations in diakinesis-metaphase I and metaphase II. The experiments were performed in two laboratories while a third laboratory participated in the chromosome evaluation. No enhancement of chromosome aberrations could be observed after acute treatment of early primary spermatocytes or chronic treatment of spermatogonia with INH.
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