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Cytogenetic investigations of mutagenic action of caffeine in premeiotic spermiogenesis in mice

✍ Scribed by Ilse-Dore Adler


Publisher
Springer
Year
1966
Tongue
English
Weight
128 KB
Volume
3
Category
Article
ISSN
0340-6717

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The chromosome-damaging effect of 6-mercaptopurine (6-MP) was investigated in bone marrow cells of rats, Chinese hamsters, and mice after single intraperitoneal injections of doses from 3.125 to 250 mg/kg, and after multiple applications of 10, 25, 50, and 125 mg/kg. The optimal time of investigatio