A major goal in pre-clinical cancer chemoprevention research is to assess the predictive value of intermediate biomarker modulation towards tumor prevention. With this aim, BALB/c mice were treated with 10 daily i.p. injections of urethane (ethyl carbamate), each of 400 mg/kg body weight. Groups of
✦ LIBER ✦
Cytogenetic characteristics of lung tumors induced in BALB/c mice by transplacental action of N-nitrosoethylurea
✍ Scribed by A. Ya. Likhachev
- Publisher
- Springer US
- Year
- 1976
- Tongue
- English
- Weight
- 530 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0007-4888
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## Abstract Lung cancer is the most important cause of death among neoplastic diseases worldwide, and cigarette smoke (CS) is the major risk factor for cancer. Complementarily to avoidance of exposure to CS, chemoprevention will lower the risk of cancer in passive smokers, ex‐smokers, and addicted