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Cytogenetic, FISH, and molecular studies in a case of B-cell chronic lymphocytic leukemia with karyotypic evolution

✍ Scribed by Christian Chena; Roxana Cerretini; María Fernanda Noriega; Marina Narbaitz; Mariano Scolnik; María Fernanda Palacios; Daniela Neme; Salvador Bruno; Irma Slavutsky


Book ID
114423171
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
176 KB
Volume
69
Category
Article
ISSN
0902-4441

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The t(14;19)(q32.3;q13.1) is a recurring translocation found in the neoplastic cells of some patients with chronic lymphocytic leukemia (CLL) or other B-lymphocytic neoplasms. We previously cloned the translocation breakpoint junctions present in the leukemic cells from three such patients and ident