Cytogenetic findings in terminal large cell transformation in a case of sézary syndrome
✍ Scribed by Elvira D'Alessandro; Andrea De Pasquale; Claudio Ligas; Maria Luisa Lo Re; Mario Di Cola; Giuseppe Del Porto; Dennis Quaglino
- Book ID
- 119105399
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 398 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0165-4608
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Sézary's syndrome (SS) is a leukaemic variant of mycosis fungoides, a cutaneous T-cell lymphoma showing distinct clinical, histological, immunological, and genotypic features. We report a 10-year follow-up of a patient with SS exhibiting unusual features such as granulomatous skin lesions, transform
## Background: Data on genome-wide surveys for chromosome aberrations in primary cutaneous t-cell lymphoma (ctcl) are limited. ## Objective: To investigate genetic aberrations in ctcl. ## Methods: We analysed 18 cases of sézary syndrome (ss) and 16 cases of mycosis fungoides (mf) by comparative