A case of Sézary's syndrome associated with granulomatous lesions, myelodysplastic syndrome and transformation into CD30-positive large-cell pleomorphic lymphoma

✍ Scribed by P.M. Carrozza; W. Kempf; D.V. Kazakov; R. Dummer; G. Burg

• Publisher: John Wiley and Sons
• Year: 2002
• Tongue: English
• Weight: 189 KB
• Volume: 147
• Category: Article
• ISSN: 0007-0963
• DOI: 10.1046/j.1365-2133.2002.04839.x

✦ Synopsis

Sézary's syndrome (SS) is a leukaemic variant of mycosis fungoides, a cutaneous T-cell lymphoma showing distinct clinical, histological, immunological, and genotypic features. We report a 10-year follow-up of a patient with SS exhibiting unusual features such as granulomatous skin lesions, transformation to a CD30-positive large-cell pleomorphic T-cell lymphoma, and development of myelodysplastic syndrome and review the cases of SS reported in the literature with these unusual and rare complications.