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Cytogenetic effects induced by organophosphorus pesticides in mouse spermatocytes

✍ Scribed by Degraeve, Noël; Chollet, Marie-Christine; Moutschen, Jean

Book ID
123397207
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
283 KB
Volume
21
Category
Article
ISSN
0378-4274

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The genotoxic effects of griseofulvin (GF) in mouse primary spermatocytes at diakinesis metaphase I of meiosis were investigated. Griseofulvin was administered orally as a single dose of 500, 1000, 1500 and 2000 mg kg-' body wt. and a multiple treatment with a daily dose of 1009 mg kg-' body wt. for