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Cytogenetic characterization of complex karyotypes in seven established melanoma cell lines by multiplex fluorescence in situ hybridization and DAPI banding

✍ Scribed by Hans-Jürgen Schulten; Bastian Gunawan; Friedrich Otto; René Hassmann; Christian Hallermann; Albrecht Noebel; László Füzesi


Book ID
114135247
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
300 KB
Volume
133
Category
Article
ISSN
0165-4608

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Several nonrandom recurrent chromosomal changes are observed in uveal melanoma. Some of these abnormalities, e.g., loss of chromosome 3, gain of the q arm of chromosome 8, and chromosome 6 abnormalities, are of prognostic value. Cytogenetic analysis and/or fluorescence in situ hybridization (FISH) a