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Cytogenetic changes in human lymphoma U-937 induced to apoptosis by tumor necrosis factor

✍ Scribed by Kovalova, O. A.; Yasinskiy, Ya. S.; Bezdeneznykh, N. A.; Kudryavets, Yu. I.

Book ID
125395977
Publisher
Pleiades Publishing
Year
2014
Tongue
English
Weight
496 KB
Volume
8
Category
Article
ISSN
1990-519X

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Tumor necrosis factor-a (TNF-a) is a cytokine that induces apoptosis in various cell systems by binding to the TNF receptor (TNFR). To study TNF-a-induced apoptosis, we isolated and characterized a novel TNF-a-resistant variant, U937/ TNF clone UA, from human monocytic leukemia U937 cells. The UA ce