Cytogenetic and radiation hybrid mapping reveals conserved synteny and gene order between human Chromosome 21 and pig Chromosome 13
✍ Scribed by Christopher K. Tuggle; Carine Genêt; Xian-Wei Shi; Patrick Chardon; Ibis Sanchez-Serrano; Grant Cravens; Denis Milan; Martine Yerle
- Publisher
- Springer-Verlag
- Year
- 2001
- Tongue
- English
- Weight
- 176 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0938-8990
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Previous comparative mapping suggested that at least five pig chromosomes (Sscr4, 6, 9, 10 and 14) share homology with human chromosome 1 (Hsap1). A significant quantitative trait loci (QTL) for fat deposition has been identified on Sscr4 that appears to be near the junction region between Sscr4 and
## Summary Comparative mapping studies facilitate the identification of genes located in quantitative trait locus (QTL) regions in domestic animals by utilizing information from the human genome. Radiation hybrid (RH) mapping is effective for this purpose because of its high resolution in ordered g