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Cytogenetic and molecular analysis of early stage renal cell carcinomas in a family with a translocation (2;3)(q35;q21)

✍ Scribed by Danielle Bodmer; Marc Eleveld; Marjolijn Ligtenberg; Marian Weterman; Adrian van der Meijden; Marianne Koolen; Christien Hulsbergen-van der Kaa; Arie Smits; Dominique Smeets; Ad Geurts van Kessel


Book ID
114135248
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
376 KB
Volume
134
Category
Article
ISSN
0165-4608

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Disruption of a novel gene, DIRC3, and e
✍ DaniΓ«lle Bodmer; Marga Schepens; Marc J. Eleveld; Eric F.P.M. Schoenmakers; Ad G πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 194 KB

## Abstract Previously, we identified a family with renal cell cancer and a t(2;3)(q35;q21). Positional cloning of the chromosome 3 breakpoint led to the identification of a novel gene, __DIRC2__, that spans this breakpoint. Here we have characterized the chromosome 2 breakpoint in detail and found