Cytogenetic and cytokinetic analysis of lymphocytes from patients with hereditary adenomatosis of the colon and rectum
β Scribed by Toshihiko Kasukawa; Toshiaki Watanabe; Akira Endo
- Book ID
- 119102984
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 379 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0165-4608
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## Abstract A human colon carcinoma cell line was established from a metastatic lymph node of a patient with hereditary adenomatosis of the colon and rectum (ACR). Cells of this line, designated KMSβ4, have been continuously propagated in culture during the past 24 months. The cells growing on the
## Abstract Chemical transformation of cultured human skin fibroblasts (PF) derived from individuals with hereditary adenomatosis of the colon and rectum is reported. Cells treated only with various levels of NβmethylβNβ²βnitroβNβnitrosoguanidine (MNNG) underwent morphological alteration. The morpho
## Abstract A heritable propensity to develop malignant lesions is found in individuals with familial adenomatosis of the colon and rectum (ACR) and the Gardner's syndrome variant, an autosomal dominant trait. In the present study, the growth characteristics of cultured skin fibroblasts (SF) derive