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CytochromeP450isoforms involved in melatonin metabolism in human liver microsomes

✍ Scribed by Gabriella Facciolá; Mats Hidestrand; Christer von Bahr; Gunnel Tybring

Publisher
Springer
Year
2001
Tongue
English
Weight
146 KB
Volume
56
Category
Article
ISSN
0031-6970

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## Abstract Previous studies have established that chlorpyrifos (CPS), fipronil, and nonane can all be metabolized by human liver microsomes (HLM) and a number of cytochrome P450 (CYP) isoforms. However, metabolic interactions between these three substrates have not been described. In this study th