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Cytochrome P450/NADPH-dependent formation of trans epoxides from trans-arachidonic acids

✍ Scribed by Uzzal Roy; Olivier Loreau; Michael Balazy


Book ID
108073172
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
155 KB
Volume
14
Category
Article
ISSN
0960-894X

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## Abstract Aristolochic acid (AA), a naturally occurring nephrotoxin and carcinogen, has been associated with the development of urothelial cancer in humans. Understanding which human enzymes are involved in AA activation and/or detoxication is important in the assessment of an individual's suscep