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Cytochrome P-450-dependent formation of isoandrocymbine from autumnaline in colchicine biosynthesis

✍ Scribed by Amber Nasreen; Martina Rueffer; Meinhart H. Zenk


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
228 KB
Volume
37
Category
Article
ISSN
0040-4039

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## Abstract **Two new models** for cytochrome P450 in which the thiolate axial ligand is replaced by an RSO~3~^βˆ’^ group, form oxo‐iron(IV) porphyrin π‐cation radicals as sole oxidation products in β€œperoxo shunt” reactions (see scheme) independent of the nature of the employed solvent (polar or non‐