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Cytochrome P450IID6-mediated oxidation and acute neuroleptic-induced adverse effects

โœ Scribed by SPINA, E


Book ID
123534309
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
69 KB
Volume
26
Category
Article
ISSN
1043-6618

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Dextromethorphan (DXM) is commonly used as a probe for the metabolic activity of the debrisoquine isozyme (P-450 lID6) of the cytochrome P-450 mixed-function oxidase system. Several reports have described changes in P-450 activity with dietary alteration. This study was conducted to determine the ef