Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells
β Scribed by Arthur I Cederbaum
- Book ID
- 108951071
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 101 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0815-9319
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π SIMILAR VOLUMES
This study investigated the role of cytochrome P-450 2E1 in enhanced microsomal lipid peroxidation in experimental alcoholic liver disease. W e also examined the contribution of this isoform to the increased microsomal injury in alcoholic liver disease caused by carbon tetrachlorideinduced or iron-i
The release of proinflammatory cytokines by endotoxins and during oxidative stress is considered to be an early key step in the pathogenesis of alcoholic liver disease (ALD). Ethanol-inducible cytochrome P450 2E1 (CYP2E1) has potentially pro-oxidative and toxicological properties, and its expression