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Cytochrome P2A13 and P1A1 gene polymorphisms are associated with the occurrence of uterine leiomyoma

✍ Scribed by D. Herr; H. Bettendorf; D. Denschlag; C. Keck; D. Pietrowski

Publisher
Springer
Year
2006
Tongue
English
Weight
229 KB
Volume
274
Category
Article
ISSN
0003-9128

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## Abstract Pathogenetically, uterine leiomyomas (ULs) can be interpreted as the result of a monoclonal abnormal proliferation of myometrial cells. Oncogene‐induced senescence (OIS) is a frequent phenomenon in premalignant lesions that leads to a growth arrest mainly by the activation of two potent