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Polymorphic variation of CYP1A1 is associated with the risk of gastric cardia cancer: a prospective case–cohort study of cytochrome P-450 1A1 and GST enzymes

✍ Scribed by Mark J. Roth; Christian C. Abnet; Laura Lee Johnson; Steven D. Mark; Zhi Wei Dong; Philip R. Taylor; Sanford M. Dawsey; You-Lin Qiao

Publisher
Springer Netherlands
Year
2004
Tongue
English
Weight
97 KB
Volume
15
Category
Article
ISSN
0957-5243

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## Abstract Genetic backgrounds may modify the association of environmental tobacco smoke (ETS) with lung cancer risk. Polymorphisms of both the activating and detoxifying enzymes, cytochrome P4501A1 (CYP1A1) and glutathione‐S‐transferase M1 (GSTM1), may be important as genetic factors. We conducte