Cystic fibrosis and CFTR
โ Scribed by R. Greger; R. Schreiber; M. Mall; A. Wissner; A. Hopf; M. Briel; M. Bleich; R. Warth; K. Kunzelmann
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 40 KB
- Volume
- 443
- Category
- Article
- ISSN
- 0031-6768
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๐ SIMILAR VOLUMES
In order to facilitate the screening for the less common mutations in the cystic fibrosis (CF) gene viz., the CF transmembrane conductance regulator gene (CFTR), marker haplotypes were determined for German non-CF (N) and CF chromosomes by polymerase chain reaction analysis of four polymorphisms ups
Cystic fibrosis (CF) is characterized by defective Cl -and enhanced Na + conductance, both due to malfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) protein in airway epithelial cells. In the present study we examined whether expression of CFTR mRNA (CFTR messenger ribonuc
## Communicated by Claude Ferec Cystic fibrosis (CF) is mainly caused by mutations that interfere with the biosynthetic folding of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. The aim of this study was to determine the mechanism of dysfunction of a disease-causi