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Cysteine and serine proteases in colorectal cancer

✍ Scribed by Herszényi, L.; Plebani, M.; Carraro, P.; De Paoli, M.; Roveroni, G.; Cardin, R.; Tulassay, Zs.; Naccarato, R.; Farinati, F.

Book ID
122723277
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
161 KB
Volume
114
Category
Article
ISSN
0016-5085

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## BACKGROUND. Cathepsin B (CATB) and cathepsin L (CATL), which are cysteine proteases, urokinase-(UPA) and tissue-type plasminogen activator (TPA), both serine proteases, and their inhibitor type-1 (PAI-1) are believed to play an important role in colorectal carcinoma (CRC) invasion and metastasi