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Cystals and cross-linked enzyme crystals (CLEC)of fungal and bacterial lipases and correction of canine pancreatic steatorrhea

โœ Scribed by Sandberg, Rodney J.; Margolin, Alexey L.; Shenoy, Bhami C.; DiMagno, Eugene P.


Book ID
122854132
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
174 KB
Volume
118
Category
Article
ISSN
0016-5085

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Cofactor-Bound Cross-Linked Enzyme Cryst
โœ Nancy St. Clair; Yi-Fong Wang; Alexey L. Margolin ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 104 KB

In conclusion, this total synthesis of ()-discodermolide proceeds in 27 steps and 7.7 % overall yield for the longest linear sequence starting from commercial methyl (S)-3hydroxy-2-methylpropionate. The three key subunits were synthesized efficiently using boron-mediated anti-selective aldol reactio