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CYP1A1 Ile462Val is a risk factor for ovarian cancer development

โœ Scribed by Miaoling Huang; Qing Chen; Jianpeng Xiao; Xiaomiao Zhao; Changhao Liu


Book ID
116400569
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
491 KB
Volume
58
Category
Article
ISSN
1043-4666

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## Abstract ## BACKGROUND. In estrogen biosynthetic pathways, many enzymes are important for metabolism, detoxification, and bioavailability. Polymorphisms in these genes may have an effect on the enzymes' function. For example, higher expression and activation of biosynthetic enzymes and lower ex