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CYP17 promoter polymorphism and breast cancer risk in males and females in relation to BRCA2 status

✍ Scribed by Gudmundsdottir, K; Thorlacius, S; Jonasson, J G; Sigfusson, B F; Tryggvadottir, L; Eyfjord, J E


Book ID
109997522
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
78 KB
Volume
88
Category
Article
ISSN
0007-0920

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Long-term exposure to oestrogens is a well-recognised risk factor for breast cancer, whereas little is known about the influence of polymorphisms of genes involved in oestrogen biosynthesis and metabolism. A candidate, containing a single bp polymorphism, T8C, (designated, A2 allele), might be the C