Cyclosporine A in the treatment of aplastic anemia
β Scribed by I. L. Mackenzie; A. Manoharan
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 107 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0361-8609
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The development of alloantibodies to platelets is a major problem in the supportive management of thrombocytopenia in patients with severe aplastic anemia. We report here a case of aplastic anemia refractory to platelet transfusion. An immunosuppressant, cyclosporin A, which was used for the therapy
Diamond-Blackfan anemia (DBA) is characterized by a variable response to corticosteroid therapy. Patients poorly responsive to acceptable doses of steroid treatment require long-term transfusion therapy. We have treated three patients with DBA with the immunosuppressive agent cyclosporin A with limi