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Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA

✍ Scribed by LUCEY, M

Book ID
122728191
Publisher
The Lancet
Year
1990
Tongue
English
Weight
723 KB
Volume
335
Category
Article
ISSN
0140-6736

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We have investigated the importance of cytochrome P-45OIIIA enzyme activity in influencing dosage of the immunosuppressive drugs FK 506 and cyclosporine after liver transplantation. Cytochrome P-45OIIIA enzyme activity in uiuo was measured 1 yr postoperatively in 37 stable orthotopic liver graft rec