Mbar a linear extrapolation (dasheine) to a maxumum loading force of 7000 N produced a central pressure of 2.8 Mbar. This method is similar but superior to conventional methods of ultrahigh-pressure calibration because it in- corporates supporting data at radial dis- tances. In the second method th
β¦ LIBER β¦
Cyclophilin: a specific cytosolic binding protein for cyclosporin A
β Scribed by Handschumacher, R.; Harding, M.; Rice, J; Drugge, R.; Speicher, D.
- Book ID
- 111679022
- Publisher
- American Association for the Advancement of Science
- Year
- 1984
- Tongue
- English
- Weight
- 1002 KB
- Volume
- 226
- Category
- Article
- ISSN
- 0036-8075
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Human cyclophilin A (hCypA) contains one tryptophan residue at position 121 (Trp121). The fluorescence intensity of this single tryptophan residue doubles upon binding the clinically important immunosuppressant cyclosporin A (CsA). Trp121 is in close contact to the bound CsA and is well-conserved in