Seven purified cyclosporine (CsA) metabolites were analyzed for binding to cyciophilin and to a 50 kDa protein purified from a JURKAT cell line. In addition, the potency of the seven metabolites, relative to CsA, was obtained using a primary mixed lymphocyte culture (MLC) suppression assay. CsA, M1,
Interaction of cyclosporin A and two cyclosporin analogs with cyclophilin: relationship between structure and binding
✍ Scribed by Gabrielle Zeder-Lutz; Marc H.V. Van Regenmortel; Roland Wenger; Danièle Altschuh
- Publisher
- Elsevier Science
- Year
- 1994
- Weight
- 563 KB
- Volume
- 662
- Category
- Article
- ISSN
- 0378-4347
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