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Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer’s Disease neuropathology

✍ Scribed by Zhongmin Xiang; Lap Ho; Jennifer Valdellon; David Borchelt; Kevin Kelley; Lauren Spielman; Paul S. Aisen; Giulio Maria Pasinetti


Book ID
117412227
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
226 KB
Volume
23
Category
Article
ISSN
0197-4580

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## Abstract The cerebral deposition of amyloid β‐peptide, a central event in Alzheimer's disease (AD) pathogenesis, begins several years before the onset of clinical symptoms. Noninvasive detection of AD pathology at this initial stage would facilitate intervention and enhance treatment success. In