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Cyclooxygenase-2 Expression Induced by Photofrin Photodynamic Therapy Involves the p38 MAPK Pathway

โœ Scribed by Marian Luna; Sam Wong; Angela Ferrario; Charles J. Gomer


Book ID
111413183
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
425 KB
Volume
84
Category
Article
ISSN
0031-8655

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Neurotoxic prostaglandin J2 enhances cyc
โœ Zongmin Li; Marlon Jansen; Kenyon Ogburn; Laura Salvatierra; Lavonne Hunter; Sne ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 810 KB

## Abstract The role of the proinflammatory and inducible form of cyclooxygenases (COXโ€2) in neurodegeneration is not well defined. Some of its metabolic products, such as prostaglandins (PG) of the J2 series, are known to be neurotoxic. Here we demonstrate that PGJ2 enhances COXโ€2 gene expression