Neurotoxic prostaglandin J2 enhances cyc
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Zongmin Li; Marlon Jansen; Kenyon Ogburn; Laura Salvatierra; Lavonne Hunter; Sne
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Article
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2004
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John Wiley and Sons
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English
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## Abstract The role of the proinflammatory and inducible form of cyclooxygenases (COXโ2) in neurodegeneration is not well defined. Some of its metabolic products, such as prostaglandins (PG) of the J2 series, are known to be neurotoxic. Here we demonstrate that PGJ2 enhances COXโ2 gene expression