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3P-0697 Induction of cyclooxygenase-2 by lysophosphatidylcholine in vascular smooth muscle cells: Involvement of p42/44 and p38MAPK pathway

✍ Scribed by Yamakawa, T.; Tanaka, S.; Okuda, K.; Sekihara, H.


Book ID
118632305
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
78 KB
Volume
4
Category
Article
ISSN
1567-5688

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## Abstract Sphingosine 1‐phosphate (S1P) has been shown to regulate smooth muscle cell proliferation, migration, and vascular maturation. S1P increases the expression of several proteins including COX‐2 in vascular smooth muscle cells (VSMCs) and contributes to arteriosclerosis. However, the mecha