Cyclooxygenase-2 and Bcl-2 expression in the stomach mucosa of Wistar rats exposed toHelicobacter pylori,N′-methyl-N′-nitro-N-nitrosoguanidine and bile
✍ Scribed by Loogna, Peter; Franzén, Lennart; Sipponen, Pentti; Domellöf, Lennart
- Book ID
- 113042082
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 220 KB
- Volume
- 441
- Category
- Article
- ISSN
- 1432-2307
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The effect of prolonged administration of a rat C-erbB-2/ neu (C-erbB-2) antisense oligonucleotide on gastric carcinogenesis induced by N-methyl-NЈ-nitro-N-nitrosoguanidine (MNNG) and on the labeling and apoptotic indices of gastric cancer was examined in Wistar rats After oral treatment with MNNG f
We previously suggested that hydroxyl free radical (•OH) production may play a role in carcinogenesis induced by N-methyl-NЈ-nitro-N-nitrosoguanidine (MNNG). MNNGinduced gastric cancer in rats and human gastric carcinoma occur most often in the antral mucosa and rarely in the normal fundic mucosa. W